Angiotensin is a peptide that causes vasoconstriction and a subsequent increase in blood pressure. It is part of the renin-angiotensin system, which is a major target for drugs that lower blood pressure. Angiotensin also stimulates the release of aldosterone, from the adrenal cortex. Aldosterone promotes sodium retention in the distal nephron, in the kidney, which also drives blood pressure up.
Angiotensin is an oligopeptide and is apowerful dipsogen. It is derived from the precursor molecule angiotensinogen, a serum globulin produced in the liver. It plays an important role in the renin-angiotensin system.
Angiotensin is an oligopeptide and is a hormone and a powerful dipsogen. It is derived from the precursor molecule angiotensinogen, a serum globulin produced in the liver. It plays an important role in the renin-angiotensin system. Angiotensin was independently isolated in Indianapolis and Argentina in the late 1930s (as 'angiotonin' and 'hypertensin', respectively) and subsequently characterised and synthesized by groups at the Cleveland Clinic and Ciba laboratories in Basel, Switzerland
Application:
Angiotensin I is converted to angiotensin II (AII) through removal of two C-terminal residues by the enzyme angiotensin-converting enzyme (ACE), primarily through ACE within the lung (but also present in endothelial cells and kidney epithelial cells). ACE found in other tissues of the body has no physiological role (ACE has a high density in the lung, but activation here promotes no vasoconstriction, angiotensin II is below physiological levels of action).[citation needed] Angiotensin II acts as an endocrine, autocrine/paracrine, and intracrine hormone.
F.A.Q
1:Can I get some samples before bulk order?
Yes, we can supply the free sample, but the shipping cost be paid by customers.
2: How to start orders or make payments?
PI will be sent first after confirmation of order,enclosed our bank information.Payment by T/T, Western Union, L/C.
3: What's your MOQ?
Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid. It depends on the product.
4: How about delivery leadtime?
Delivery lead time: About 3-5 workdays after payment confirmed.
5: How to contact us ?
You can chat with us by Trademanager, WhatsApp&Skype Online.
You can dial our telephone directly or send E-mail to us and you will get our reply.
Our Service
1.Cooperate with research institutions, we strictly control the process from raw material to finished product.
2.The customer comes first, we provide reasonable price, high quality product and prompt shipment.
3.We can send the goods to your delivery address directly. It is relatively safe and fast.
4.Quick and clear response to customers questions.
5.We could make our price discount if you place a substantial order with us.
Our company's strengths
1.Our products are of high quality and the price is competitive.
2. Standard: BP/USP/EP/ enterprise standard.
All purities ≥99%
3. Fast and safe delivery and careful shipment, a variety of transportation modes for you to choose.
Customs clearance rate is 99% or higher.
Packing & Transportation
Transportation:Door to Door
Shipping can be DHL, UPS, TNT, EMS, Fedex, etc.
For large orders, they will be delivered by air or sea.
We have special transportation channels.
Our Advantages
Why Choose US?
1. Selecting raw materials strictly,our products are the highest purity.
2.Reasonable and competitive price. Provide the best and professional service.
3.Fast delivery of the samples ,samples from stock. Reliable shipping way.
4.Full experience of large numbers containers loading in Chinese sea port.
5. Best after-service after shipment .
6. Professional documents for your custom clearance.
Company profile:
Wuhan Newtop Biotech Co., Ltd is located in Hubei province of China. We specialized in active pharmaceutical ingredient, pharmaceutical intermediates,veterinary drugs and agrochemicals.We have strong professional research and development team, talented personnel and completely equipped laboratory for the quality controlling.Our products are exported to more than 60 countries overseas, 80% of which are exported to Europe and America, and 20% to Southeast Asia, the Middle East, South Africa and other regions. Because of excellent quality and after-sales service, our company has gained a good reputation at home and abroad."Quality Best,Customer First" is what we adhering,sincerely looking forward to establish long-term and mutual beneficial business relationship with worldwide customers.
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