| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
|
Still deciding? Get samples of US$ 1/Piece
Request Sample
|
Suppliers with verified business licenses
Audited Supplier Audited by an independent third-party inspection agency
Welcome to visit our company Wuhan Newtop Biotech Co., Ltd
Aviptadil
|
Product Name
|
Aviptadil |
|
CAS
|
40077-57-4 |
|
Appearance
|
White powder
|
|
Assay
|
Above 99%
|
|
Test
|
HPLC
|
|
Certificate
|
ISO 9001
|
|
Storage Temperature
|
Keep in a cool, dry, dark location in a tightly sealed container or cylinder.
|
VIP is extensively distributed in central and peripheral tissues, where it acts as a neurotransmitter and neuromodulator.8 The main activity of VIP is vasodilatation. VIP induces the dilation of vessels, which results in increased blood flow, decreased peripheral vascular resistance, and hypotension. While VIP has a suppressive effect on the intestinal smooth muscle, it exerts relaxant effects on the lower esophageal sphincter, the sphincter of Oddi, the anal sphincter, and the bronchial smooth muscle. In the small intestine, VIP facilitates the secretion of electrolytes and aqueous liquid. In the stomach, it inhibits gastric secretion. In the pancreas, VIP facilitates the external secretion of bicarbonic acid and aqueous liquid from pancreatic epithelial cells, and facilitates enzyme secretion from acinar cells. VIP promotes the secretion of glucagon in a glucose-dependent manner. VIP is broadly distributed in the central nervous system, especially in the hypothalamus and pituitary anterior lobe, and is associated with the regulation of pituitary hormones. VIP is produced by lymphoid tissue and exerts a wide spectrum of immunological functions, controlling the homeostasis of the immune system through different receptors expressed in various immunocompetent cells. It functions as a proliferative factor in normal tissue cells as well as in cancer cells.
Our Raw Materia Factory
Upstream peptide synthesis
Wuhan Newtop Biotech Co., Ltd production plants are endowed with state-of-the-art equipment for solvent supply, peptide synthesis, purification and isolation of active ingredients and intermediates. All equipment and containment is GMP qualified and cleaning validated. Overlapping capacities and sizes of different equipment trains facilitate a smooth scale-up for increases in demand within the product life cycle.
Downstream purification and isolation of peptides
Wuhan Newtop Biotech Co., Ltd is committed to the systematic expansion and modernization of its purification equipment in order to ensure the efficient production of ever-increasing amounts of bulk peptide pharmaceuticals.It uses sophisticated methods for large scale purification campaigns such as preparative high performance liquid chromatography (HPLC), ion exchange (IEX), size-exclusion chromatography (SEC), and ultra-filtration (UF/TFF). The equipment in place permits highly efficient or even continuous manufacturing of extremely pure products up to multi-kg quantities per lot.For preparative HPLC, dynamic axial compression (DAC) stainless steel columns of up to 60 cm diameter both in batch and continuous mode are packed with the appropriate high performance silica separation phase. For low-pressure chromatography columns up to 80 cm diameter are available. Solvent delivery is ensured from eluent tank farms and containers.The control of microbiological contamination is a prerequisite for API manufacturing. Class D (ISO 8) and C (ISO 7) clean rooms are supplied via HEPA-filtered, temperature and humidity controlled air, down-flow booths are used for minimizing microbial contamination and protecting operators. Highly active pharmaceutical ingredients are handled in integrated safety workbenches or flexible isolators reaching OEB level 4 (1-10 µg/m3).Predefined physicochemical properties of the API can only be achieved by a carefully controlled isolation process. Besides precipitation and crystallization, lyophilization of intermediates and final API is a standard unit operation.
Our R&D Laboratories
We have sufficient inventory to ensure delivery speed
| If you have any other questions , please feel free to contact with us. |
| Q:Are you a trading company or a manufacturer? |
| A:We are both, so we can always provide wholesale price and most products in stock. |
| Q:How should I pay? |
| A:We accept Bank Transfer and Western union etc. |
| Q:About the delivery |
| A:shipping method are DHL/USPS/FedEx,Delivery time 1-3 working days. |
| Q1:Will you supply samples for testing? |
| A: Free samples for the quality evaluation for most products, but customers only need to undertake the shipping fee for delivery the samples to your door. |
| Q2:What's your MOQ? |
| A: For the high value product, our MOQ starts from 10g,100g and 1kg. |
| Q3:Which kind of payment terms do you accept? |
| A: Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment |
| by T/T, Western Union ). Bulk order by T/T or L/C. |
| Q4:How about your delivery time? |
| A: Generally, it will take 3 to 5 days after receiving your advance payment. |
| Q5:How do you treat quality complaint? |
| A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss. |
){kind=link}