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Product Name
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Chloramphenicol |
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CAS
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56-75-7 |
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Appearance
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White powder |
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MF
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C11H12Cl2N2O5 |
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Molecular Weight
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323.13 |
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Purity
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99%
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Storage
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Keep in a cool, dry, dark location in a tightly sealed container or cylinder
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Shelf Life
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24 Months
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Chloramphenicol, also known as chlornitromycin, is a broad-spectrum, bacteriostatic antibiotic derived from Streptomyces venezuelae. It is first isolated from cultures of Streptomyces venequelae in 1947 but now produced synthetically. The synthetic product is racemic, also called synthomycin. Syntomycin is a mixture of chloramphenicol L-isomer and d-isomer. Because of dextroisomer antibacterial effect, the effect of synthomycin is only half of the natural products. It has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. It is effective against several gram-positive and gram-negative bacteria and commonly used in researching protein synthesis and to select for chloramphenicol-resistant transformed cells or the bacterial CAT gene.
Chloramphenicol is a semisynthetic, broad-spectrum antibiotic derived from Streptomyces venequelae with primarily bacteriostatic activity. Chloramphenicol diffuses through the bacterial cell wall and reversibly binds to the bacterial 50S ribosomal subunit. The binding interferes with peptidyl transferase activity, thereby prevents transfer of amino acids to the growing peptide chains and blocks peptide bond formation. As a result bacterial protein synthesis is blocked and impede bacterial cell proliferation.
Chloramphenicol is an organochlorine compound that is dichloro-substituted acetamide containing a ring, an amide bond and two alcohol functions. It has a role as an antimicrobial agent, an antibacterial drug, a protein synthesis inhibitor, an Escherichia coli metabolite, a Mycoplasma genitalium metabolite and a geroprotector. It is an organochlorine compound, a diol, a C-nitro compound and a carboxamide.
Wuhan Newtop Biotech Co., Ltd is a professional chemical raw materials manufacturer with many years experince,Our company specializes in exporting high quality Pharmaceutical intermediates,Pharmaceutical raw materials,Safe Organic Solvents, Plant Extract, Spice Auxiliary and Hormones.We have our own delivery line to Canada,USA,UK ,Spain,
Netherland,Germany,Russia,Kazakhstan,
Ukraine,etc. Door to door without any customs clearance issues.Our products are produced on the basis of best technical team, advanced equipment, high qualified management which meet the requirements of security and environmental protection.
Our Raw Materia Factory
Upstream peptide synthesis
Wuhan Newtop Biotech Co., Ltd production plants are endowed with state-of-the-art equipment for solvent supply, peptide synthesis, purification and isolation of active ingredients and intermediates. All equipment and containment is GMP qualified and cleaning validated. Overlapping capacities and sizes of different equipment trains facilitate a smooth scale-up for increases in demand within the product life cycle.
Downstream purification and isolation of peptides
Wuhan Newtop Biotech Co., Ltd is committed to the systematic expansion and modernization of its purification equipment in order to ensure the efficient production of ever-increasing amounts of bulk peptide pharmaceuticals.It uses sophisticated methods for large scale purification campaigns such as preparative high performance liquid chromatography (HPLC), ion exchange (IEX), size-exclusion chromatography (SEC), and ultra-filtration (UF/TFF). The equipment in place permits highly efficient or even continuous manufacturing of extremely pure products up to multi-kg quantities per lot.For preparative HPLC, dynamic axial compression (DAC) stainless steel columns of up to 60 cm diameter both in batch and continuous mode are packed with the appropriate high performance silica separation phase. For low-pressure chromatography columns up to 80 cm diameter are available. Solvent delivery is ensured from eluent tank farms and containers.The control of microbiological contamination is a prerequisite for API manufacturing. Class D (ISO 8) and C (ISO 7) clean rooms are supplied via HEPA-filtered, temperature and humidity controlled air, down-flow booths are used for minimizing microbial contamination and protecting operators. Highly active pharmaceutical ingredients are handled in integrated safety workbenches or flexible isolators reaching OEB level 4 (1-10 µg/m3).Predefined physicochemical properties of the API can only be achieved by a carefully controlled isolation process. Besides precipitation and crystallization, lyophilization of intermediates and final API is a standard unit operation.
Our R&D Laboratories
Wuhan Newtop Biotech Co., Ltd acquired early mastery of development and manufacturing of peptides, the short chain amino acids linked by peptide bonds that have enabled new generations of small molecule drugs that closely mimic the body's natural pathways.Wuhan Newtop Biotech Co., Ltd possesses first-class capabilities to manufacture peptides at industrial scale and in full compliance with the strictest Good Manufacturing Practice (GMP) standards.
| If you have any other questions , please feel free to contact with us. |
| |
| Q:Are you a trading company or a manufacturer? |
| A:We are both, so we can always provide wholesale price and most products in stock. |
| |
| Q:How should I pay? |
| A:We accept Bank Transfer and Western union etc. |
| |
| Q:About the delivery |
| A:shipping method are DHL/USPS/FedEx,Delivery time 1-3 working days. |
| |
| Q1:Will you supply samples for testing? |
| A: Free samples for the quality evaluation for most products, but customers only need to undertake the shipping fee for delivery the samples to your door. |
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| Q2:What's your MOQ? |
| A: For the high value product, our MOQ starts from 10g,100g and 1kg. |
| |
| Q3:Which kind of payment terms do you accept? |
| A: Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment |
| by T/T, Western Union ). Bulk order by T/T or L/C. |
| |
| Q4:How about your delivery time? |
| A: Generally, it will take 3 to 5 days after receiving your advance payment. |
| |
| Q5:How do you treat quality complaint? |
| A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss. |
Welcome to be our distinguished customer, please do not hesitate to contact us!
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