| Customization: | Available |
|---|---|
| Powder: | Yes |
| Customized: | Customized |
|
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| Sample | Free Sample |
| Delivery | 1 Week |
| Specification | 99% |
| Origin | China |
| Production Capacity | 50000kg/Year |
| MOQ | 500g-1kg |
| Stock | Have Stock |
| Transport Package | Bottle, Drum, Vacuum Packed |
| Trademark | Nutriherb |
| Product Name | Abemaciclib |
| Assay | 99% Min |
| CAS | 1231929-97-7 |
| Active Ingredient | Abemaciclib |
| Grade Standard | Medicine Grade |
| Type of Product | Auxiliaries and Other Medicinal Chemicals |
| Shelf Life | 2 Years Proper Storage |
| MOQ | 1kg |
| Specification | 99% min |
| Origin | WuHan China |
| Colour | White |
| Certificate | GMP ISO USP Bp |
| Test | HPLC |
| Mf | C27h32f2n8 |
| Sample | Abemaciclib Avaliable |
| Application | API Raw Materials |
| Storage | Cool Dry Place |
| Keywords | Abemaciclib Powder |
| Transport Package | 1kg Per Foil Bag, 10 Bags Per Carton.25 Kg Per Dr |
| Trademark | Inter-Health |
| Production Capacity | 50000kg/Year |
Function :
Abemaciclib is a CD4/6 kinase inhibitor. This type of kinase is activated by connecting D-cyclin. In breast cancer cell lines that are estrogen receptor positive (HR+), cyclin D1 and CD4/ 6 It can bind to phosphorylation of retinoblastoma protein (Rb), cell cycle progression and cell proliferation. In vitro, continuous exposure to Abemaciclib inhibits Rb phosphorylation and prevents entry from G1 into the S phase of the cell cycle, leading to cell senescence and apoptosis. In breast cancer xenotransplantation models, Abemaciclib monotherapy or combined with anti-estrogens can be administered continuously every day to shrink tumors.
Application :
Abemaciclib is an orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity. It is used for the treatment of advanced or metastatic breast cancers.
| If you have any other questions , please feel free to contact with us. |
| Q:Are you a trading company or a manufacturer? |
| A:We are both, so we can always provide wholesale price and most products in stock. |
| Q:How should I pay? |
| A:We accept Bank Transfer and Western union etc. |
| Q:About the delivery |
| A:shipping method are DHL/USPS/FedEx,Delivery time 1-3 working days. |
| Q1:Will you supply samples for testing? |
| A: Free samples for the quality evaluation for most products, but customers only need to undertake the shipping fee for delivery the samples to your door. |
| Q2:What's your MOQ? |
| A: For the high value product, our MOQ starts from 10g,100g and 1kg. |
| Q3:Which kind of payment terms do you accept? |
| A: Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment |
| by T/T, Western Union ). Bulk order by T/T or L/C. |
| Q4:How about your delivery time? |
| A: Generally, it will take 3 to 5 days after receiving your advance payment. |
| Q5:How do you treat quality complaint? |
| A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss. |
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