GMP Factory 99% Purity Taltirelin Peptide CAS 103300-74-9 Door-to-Door Service

Product Details
Customization: Available
Powder: Yes
Customized: Customized
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  • GMP Factory 99% Purity Taltirelin Peptide CAS 103300-74-9 Door-to-Door Service
  • GMP Factory 99% Purity Taltirelin Peptide CAS 103300-74-9 Door-to-Door Service
  • GMP Factory 99% Purity Taltirelin Peptide CAS 103300-74-9 Door-to-Door Service
  • GMP Factory 99% Purity Taltirelin Peptide CAS 103300-74-9 Door-to-Door Service
  • GMP Factory 99% Purity Taltirelin Peptide CAS 103300-74-9 Door-to-Door Service
  • GMP Factory 99% Purity Taltirelin Peptide CAS 103300-74-9 Door-to-Door Service
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  • Overview
  • Product Description
  • Application&Function
  • Detailed Photos
  • Company Profile
  • Our Advantages
  • Packaging & Shipping
  • FAQ
Overview

Basic Info.

Model NO.
103300-74-9
Suitable for
Adult
State
Lyophilized Powder
Purity
>99%
Quality
High Purity
Top
Various Cap Color for Choose
Shelf Life
2 Year
Grade
Medical Grade
Storage Condition
2c - 8c, Well-Closed Containers
Application
Drug Peptides
Transport Package
1box
Specification
5mg/10mg/15mg
Trademark
Newtop Biotech
Origin
Wuhan
Production Capacity
500000kg

Product Description


GMP Factory 99% Purity Taltirelin Peptide CAS 103300-74-9 Door-to-Door Service                     Welcome to visit our company Wuhan Newtop Biotech Co., Ltd

Product Description

Taltirelin
Product Name
Taltirelin
MF C17H23N7O5
Appearance
White  powder
Assay
Above 99%
Test
HPLC
Certificate
ISO 9001
Storage Temperature
Keep in a cool, dry, dark location in a tightly sealed container or cylinder.
GMP Factory 99% Purity Taltirelin Peptide CAS 103300-74-9 Door-to-Door Service
GMP Factory 99% Purity Taltirelin Peptide CAS 103300-74-9 Door-to-Door Service
 
GMP Factory 99% Purity Taltirelin Peptide CAS 103300-74-9 Door-to-Door Service
Taltirelin was marketed in Japan for the treatment of neurodegenerative diseases, in particular the improvement of ataxia due to spino-cerebellar degeneration (SCD); it is the first orally-active drug in this indication. This synthetic thyrotropin-releasing hormone (TRH) analog is prepared by condensation of (S)-1-methyl-4,5-dihydroorotic acid with L-histidyl-Lprolinamide. It was shown that the S-configuration for all 3 chiral centers is crucial for CNS activity. Taltirelin is a potent agonist of the TRH receptors that shows significant effects on the cerebral monoamine systems when administered i.p. in rats. As TRH at 10-fold higher doses, taltirelin has been found to increase the extracellular levels of dopamine and its metabolites (DOPAC and HVA) as well as precursors and/or metabolites of noradrenaline and serotonin in different areas of the rat brain. Taltirelin produced an anti-ataxic activity in the Rolling mouse Nagoya, an ataxic mutant mouse. In several clinical studies performed in patients suffering from various forms of SCD, taltirelin demonstrated a statistically significant increase in the global improvement of ataxic symptoms and other neurologic abnormalities.

Application&Function

Taltirelin is an oligopeptide comprising of (4S)-1-methyl-2,6-dioxohexahydropyrimidine-4-carboxylic acid, L-histidine and L-prolinamide joined in sequence by peptide linkages. It is a thyrotropin-releasing hormone (TRH) analog. Its tetrahydrate form is approved in Japan for the treatment of spinal muscular atrophy. It has a role as a nootropic agent, a neuroprotective agent and an analgesic.

Detailed Photos

GMP Factory 99% Purity Taltirelin Peptide CAS 103300-74-9 Door-to-Door Service
GMP Factory 99% Purity Taltirelin Peptide CAS 103300-74-9 Door-to-Door Service

 

Company Profile

GMP Factory 99% Purity Taltirelin Peptide CAS 103300-74-9 Door-to-Door Service
Wuhan Newtop Biotech Co., Ltd is a professional chemical raw materials manufacturer with many years experince,Our company specializes in exporting high quality Pharmaceutical intermediates,Pharmaceutical raw materials,Safe Organic Solvents, Plant Extract, Spice Auxiliary and Hormones.We have our own delivery line to Canada,USA,UK,Spain,Netherland,
Germany,Russia,Kazakhstan,Ukraine,etc. Door to door without any customs clearance issues.Our products are produced on the basis of best technical team, advanced equipment, high qualified management which meet the requirements of security and environmental protection.

 

Our Advantages

                                         Our Raw Materia Factory

GMP Factory 99% Purity Taltirelin Peptide CAS 103300-74-9 Door-to-Door Service
GMP Factory 99% Purity Taltirelin Peptide CAS 103300-74-9 Door-to-Door Service

Upstream peptide synthesis

Wuhan Newtop Biotech Co., Ltd production plants are endowed with state-of-the-art equipment for solvent supply, peptide synthesis, purification and isolation of active ingredients and intermediates. All equipment and containment is GMP qualified and cleaning validated. Overlapping capacities and sizes of different equipment trains facilitate a smooth scale-up for increases in demand within the product life cycle. 
Downstream purification and isolation of peptides
Wuhan Newtop Biotech Co., Ltd is committed to the systematic expansion and modernization of its purification equipment in order to ensure the efficient production of ever-increasing amounts of bulk peptide pharmaceuticals.It uses sophisticated methods for large scale purification campaigns such as preparative high performance liquid chromatography (HPLC), ion exchange (IEX), size-exclusion chromatography (SEC), and ultra-filtration (UF/TFF). The equipment in place permits highly efficient or even continuous manufacturing of extremely pure products up to multi-kg quantities per lot.For preparative HPLC, dynamic axial compression (DAC) stainless steel columns of up to 60 cm diameter both in batch and continuous mode are packed with the appropriate high performance silica separation phase. For low-pressure chromatography columns up to 80 cm diameter are available. Solvent delivery is ensured from eluent tank farms and containers.The control of microbiological contamination is a prerequisite for API manufacturing. Class D (ISO 8) and C (ISO 7) clean rooms are supplied via HEPA-filtered, temperature and humidity controlled air, down-flow booths are used for minimizing microbial contamination and protecting operators. Highly active pharmaceutical ingredients are handled in integrated safety workbenches or flexible isolators reaching OEB level 4 (1-10 µg/m3).Predefined physicochemical properties of the API can only be achieved by a carefully controlled isolation process. Besides precipitation and crystallization, lyophilization of intermediates and final API is a standard unit operation.  
                                Our R&D Laboratories

GMP Factory 99% Purity Taltirelin Peptide CAS 103300-74-9 Door-to-Door Service
Wuhan Newtop Biotech Co., Ltd acquired early mastery of development and manufacturing of peptides, the short chain amino acids linked by peptide bonds that have enabled new generations of small molecule drugs that closely mimic the body's natural pathways.Wuhan Newtop Biotech Co., Ltd possesses first-class capabilities to manufacture peptides at industrial scale and in full compliance with the strictest Good Manufacturing Practice (GMP) standards.


                              We have sufficient inventory to ensure delivery speed

Packaging & Shipping

GMP Factory 99% Purity Taltirelin Peptide CAS 103300-74-9 Door-to-Door Service

FAQ

If you have any other questions , please feel free to contact with us.
 
Q:Are you a trading company or a manufacturer?
A:We are both, so we can always provide wholesale price and most products in stock.
 
Q:How should I pay?
A:We accept  Bank Transfer and Western union etc.
 
Q:About the delivery
A:shipping method are DHL/USPS/FedEx,Delivery time 1-3 working days.
 
Q1:Will you supply samples for testing?
A: Free samples for the quality evaluation for most products, but customers only need to undertake the shipping fee for delivery the samples to your door.
 
Q2:What's your MOQ?
A: For the high value product, our MOQ starts from 10g,100g and 1kg.
 
Q3:Which kind of payment terms do you accept?
A: Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment
by T/T, Western Union ). Bulk order by T/T or L/C.
 
Q4:How about your delivery time?
A: Generally, it will take 3 to 5 days after receiving your advance payment.
 
Q5:How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
Welcome to be our distinguished customer, please do not hesitate to contact us!
 

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